RT Journal Article
T1 One-Year Changes in Optic Nerve Head Parameters in Recovered COVID-19 Patients
A1 Burgos Blasco, Bárbara
A1 Güemes Villahoz, Noemi
A1 Vidal Villegas, Beatriz
A1 Martínez de la Casa, Jose Maria
A1 García Feijoo, Julián
A1 Donate López, Juan
A1 Martín Sánchez, Francisco Javier
A1 González Armengol, Juan Jorge
A1 Méndez Hernández, Carmen Dora
AB Background: The main purpose was to evaluate the changes in peripapillary retinal nerve fiber layer (RNFL) thickness and vessel density (VD) in post–COVID-19 patients during 12-month follow-up.Methods: In this prospective study, patients with COVID-19 who were attended in the Hospital Clinico San Carlos (Madrid, Spain) were included. All patients underwent a complete ophthalmological examination, optic nerve head optical coherence tomography (OCT), and OCT angiography (OCTA) using the Cirrus HD-OCT 5,000 with AngioPlex OCTA 1, 3, and 12 months after laboratory-confirmed diagnosis. Sociodemographic data, medical history, disease severity, and laboratory workup were registered.Results: A total of 180 eyes of 90 patients with SARS-CoV-2 infection were included; the mean age was 55.5 ± 8.9 years, and 46 patients (51%) were females. The mean visual acuity was 0.76 ± 0.16, and no abnormalities attributable to SARS-CoV-2 were detected in the ocular or fundus examination. No differences in the OCT and OCTA data were found between severity groups in each visit (all P > 0.05). Overall, there was a decrease in RNFL global thickness (P < 0.001) from the first to the last visit, and an increase in VD and flux index was noted in some sectors at the 12-month examination. A significant correlation was detected at 12 months between vascularization parameters and RNFL thickness.Conclusions: One year after SARS-CoV-2 infection, changes in peripapillary RNFL thickness and vascularization occur, possibly indicating a recovery in such parameters.
PB Lippincott, Williams & Wilkins ; North American Neuro-Ophthalmology Society
SN 1070-8022 ; E-ISSN: 1536-5166
YR 2022
FD 2022-12
LK https://hdl.handle.net/20.500.14352/72796
UL https://hdl.handle.net/20.500.14352/72796
LA eng
DS Docta Complutense
RD 15 may 2024