TY - JOUR AU - Fuentes, LucĂ­a AU - Wouters, K. AU - Hannou, S. A. AU - Cudejko, C. AU - Rigamonti, E. AU - Mayi, T. H. AU - Derudas, B. AU - Pattou, F. AU - Chinetti-Gbaguidi, G. AU - Staels, B. AU - Paumelle, R. PY - 2011 DO - 10.1007/s00125-011-2324-0 SN - 0012-186X SN - 1432-0428 UR - https://hdl.handle.net/20.500.14352/126030 T2 - Diabetologia AB - Aims/hypothesis Human adipose tissue macrophages (ATMs) display an alternatively activated (M2) phenotype, but are still able to produce excessive inflammatory mediators. However, the processes driving this particular ATM phenotype are not understood.... LA - eng M2 - 3150 PB - Springer Nature KW - Adipose tissue macrophage KW - CDKN2A KW - Inflammation KW - Macrophage polarisation KW - Senescence KW - Type 2 diabetes TI - Downregulation of the tumour suppressor p16INK4A contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype TY - journal article VL - 54 ER -