RT Journal Article
T1 Antibacterial PLA fibers containing thiazolium groups as wound dressing materials
A1 Echeverría, Coro
A1 Muñoz-Bonilla, Alexandra
A1 Cuervo Rodríguez, María Rocío
A1 López, Daniel
A1 Fernández-García, Marta
AB The development of inherent antimicrobial polymeric fibers can contribute to overcoming the increasing problem of infectious diseases and multiresistant microorganisms. Here, we propose the preparation of poly(lactic acid) (PLA) based electrospun fibers blended with poly[2-(4-methylthiazol-5-yl)ethyl methacrylate] (PMTA), which quaternized have proven broad spectrum antimicrobial activity either in solution or solid state. We have demonstrated that quaternized PLA/PMTA fiber mats have a remarkable antibacterial activity against S. aureus. As determined by scanning electron microscopy and Raman spectroscopy, quaternized PMTA segregates toward the outmost surface of PLA/PMTA fiber leaving the thiazolium group widely available onto the fiber surfaces, facilitating the bacteria killing by contact mode.
PB American Chemical Society
YR 2019
FD 2019
LK https://hdl.handle.net/20.500.14352/101809
UL https://hdl.handle.net/20.500.14352/101809
LA eng
NO C. Echeverría, A. Muñoz-Bonilla, R. Cuervo-Rodríguez, D. López, M. Fernández-García.  Antibacterial PLA Fibers Containing Thiazolium Groups as Wound Dressing Materials. ACS Appl. Bio Mater. 2019 Nov 4; 2 (11): 4714-4719
NO Ministerio de Economía y Competitividad (España)
NO European Commission
DS Docta Complutense
RD 10 abr 2025