TY - JOUR AU - Gámez-Chiachio, Manuel AU - Molina-Crespo, Ángela AU - Ramos-Nebot, Carmen AU - Martinez-Val, Jeannette AU - Martinez, Lidia AU - Gassner, Katja AU - Llobet, Francisco AU - Soriano, Mario AU - Hernandez, Alberto AU - Cordani, Marco AU - Bernadó-Morales, Cristina AU - Diaz, Eva AU - Rojo-Sebastian, Alejandro AU - Triviño, Juan Carlos AU - Sanchez, Laura AU - Rodríguez-Barrueco, Ruth AU - Arribas, Joaquín AU - Llobet-Navás, David AU - Sarrió, David AU - Moreno Bueno, Gema PY - 2022 DO - 10.1186/s13046-022-02497-w SN - 1756-9966 UR - https://hdl.handle.net/20.500.14352/91630 T2 - Journal of Experimental & Clinical Cancer Research AB - Background: Gasdermin B (GSDMB) over-expression promotes poor prognosis and aggressive behavior in HER2 breast cancer by increasing resistance to therapy. Decoding the molecular mechanism of GSDMB-mediated drug resistance is crucial to identify novel... LA - eng M2 - 1 PB - Springer KW - Anti-HER2 therapy KW - Drug resistance KW - Gasdermin B KW - Gastroesophageal tumors KW - HER2 breast cancer KW - LC3B KW - Protective autophagy TI - Gasdermin B over-expression modulates HER2-targeted therapy resistance by inducing protective autophagy through Rab7 activation TY - journal article VL - 41 ER -