TY - JOUR AU - Leite Fernandes, Vitor Samuel AU - López-Oliva Muñoz, María Elvira AU - Martínez Sainz, María Del Pilar AU - Agis Torres, Ángel AU - Recio Visedo, María Paz AU - Navarro Dorado, Jorge AU - Barahona Gomáriz, María Victoria AU - Benedito Castellote, Sara AU - Prieto Ocejo, Dolores AU - Climent Flórez, Belén AU - Hernández Rodríguez, Medardo Vicente PY - 2022 DO - 10.1016/j.lfs.2022.120432 SN - 0024-3205 UR - https://hdl.handle.net/20.500.14352/71526 T2 - Life Sciences AB - Aims: Nitric oxide (NO) and hydrogen sulfide (H2S) are involved in nerve-mediated corpus cavernosum (CC) relaxation. Expression of phosphodiesterase type 5 (PDE5) and type 4 (PDE4), cyclic guanosine monophosphate (cGMP)- and cyclic adenosine... LA - eng M2 - 120432 PB - Elsevier KW - Phosphodiesterase type 4 KW - cAMP signaling pathway KW - Roflumilast KW - Nerve-mediated relaxation KW - Rat corpus cavernosum TI - In vitro inhibition of phosphodiesterase type 4 enhances rat corpus cavernosum nerve-mediated relaxation induced by gasotransmitters TY - journal article VL - 296 ER -