RT Journal Article T1 HLA in Las Alpujarras Mts., South-East Spain: A Renaissance process of population artificial substitution A1 Arnaiz Villena, Antonio A1 Longas, Javier A1 Rodríguez Sainz, Carmen A1 Gómez Casado, Eduardo A1 Palacio Grüber, José Manuel de A1 Luna Gómez, Francisco A1 Moral, Pedro del A1 Suarez Trujillo, Fabio AB Spain was invaded in 711 CE by mostly Berber North Africans carrying Muslim religion to a mostly Christian/Catholic Kingdom. A fight to expel Muslims soon started and were apparently driven out of Iberia (Spain) starting in 1492 CE. However, many of these expelled people were of Iberian old ancestry that had become Muslims at Las Alpujarras Mts. (South-East Spain). Also, Muslim North Africans converted to Christianity either remained there or came back after they more definetively were expelled by 1609 CE. Las Alpujarras region was also repopulated by northern Spaniards mostly from Galicia. Our HLA study of present day Alpujarrans shows that typical North Spain and European Atlantic façade HLA extended haplotypes are very frequent in nowadays Las Alpujarras region, i. e.: HLA-(A*29-B*44)-DRB1*07:01-DQA1*02:01-DQB1*02:01 and (A*02-B*27)-DRB1*15:01-DQA1*01:02-DQB1*06:02. It is concluded that repopulation had a noticeable success even in today Alpujarran population. PB Elsevier SN 0198-8859 YR 2022 FD 2022-04-07 LK https://hdl.handle.net/20.500.14352/71482 UL https://hdl.handle.net/20.500.14352/71482 LA eng NO CRUE-CSIC (Acuerdos Transformativos 2022) DS Docta Complutense RD 4 may 2024