RT Journal Article
T1 A systematic review and meta-analysis of the serological diagnosis of Toxoplasma gondii infection highlight the lack of a One Health integrative research
A1 Huertas López, Ana
A1 Álvarez García, Gema
A1 Sánchez Sánchez, Roberto
A1 Cantos Barreda, Ana
A1 Ibáñez López, Francisco Javier
A1 Martínez Subiela, Silvia
A1 Cerón, José Joaquín
A1 Martínez-Carrasco, Carlos
AB Toxoplasma gondii is a globally distributed food-borne zoonotic parasite with numerous infection sources. The control of this zoonosis requires a One Health response that partially depends on serological monitoring in humans and animals. Herein, a systematic review and a meta-analysis were performed to analyse and compare the transdisciplinary and integrative research under the One Health approach. We searched for articles published between January 1st 2014 and September 5th 2022, focused on the development and evaluation of serological techniques for the diagnosis of T. gondii infection in humans and animals. After an exhaustive search on three scientific databases, a quality assessment was performed on 291 articles by QUADAS-2 tool, and 113 articles were finally selected. A total of 18 variables were extracted and analysed, including bibliometric characteristics, study aims and methodology. Remarkably, none of the studies included in the meta-analysis explicitly quoted the words “One Health”, and only 23.9% of them alluded to the principles underlying the One Health approach; in particular, none were conducted by physician-only teams, with the majority of these studies involving interdisciplinary research teams, followed by veterinarians and by non-physician or non-veterinarian researchers. The One Health approach followed in the serodiagnosis of T. gondii still needs further integration among scientific disciplines, which is essential to design effective control strategies.
PB Elsevier
SN 0034-5288
YR 2023
FD 2023-01-05
LK https://hdl.handle.net/20.500.14352/91566
UL https://hdl.handle.net/20.500.14352/91566
LA eng
NO Huertas-López, A., Álvarez‐García, G., Sánchez-Sánchez, R., Cantos-Barresa, A., Ibáñez-López, F. J., Martı́nez-Subiela, S., Cerón, J. J., & Martínez‐Carrasco, C. (2023). A systematic review and meta-analysis of the serological diagnosis of Toxoplasma gondii infection highlight the lack of a One Health integrative research. Research in Veterinary Science, 155, 137–149. https://doi.org/10.1016/j.rvsc.2023.01.005
NO Comunidad de Madrid
NO Fundación Séneca
NO Horizonte 2020
NO Universidad de Murcia
DS Docta Complutense
RD 6 jul 2025