TY - JOUR AU - De Tapia Hernández, Lidia Consuelo AU - García-Fojeda García-Valdecasas, María Belén AU - Kronqvist, Nina AU - Johansson, Jan AU - Casals Carro, María Cristina PY - 2022 DO - 10.3389/fimmu.2022.994328 SN - 1664-3224 UR - https://hdl.handle.net/20.500.14352/94488 T2 - Frontiers in Immunology AB - Human cathelicidin (LL-37) is a defense peptide with antimicrobial activity against various pathogens. However, LL-37 can also trigger tissue injury by binding to host cell membranes. The cytotoxic effects of LL-37 may be especially relevant in... LA - eng M2 - 994328 PB - Frontiers KW - Cathelicidin LL-37 KW - Collectin SP-A KW - Trimeric recombinant fragment KW - Antimicrobial activity KW - Cytotoxicity KW - Inflammation KW - P2X7 channel KW - Alveolar epithelial cells TI - The collectin SP-A and its trimeric recombinant fragment protect alveolar epithelial cells from the cytotoxic and proinflammatory effects of human cathelicidin in vitro TY - journal article VL - 13 ER -