RT Journal Article
T1 Pharmaceuticalmicroscale and nanoscale approaches for efficient treatment of ocular diseases
A1 Bravo Osuna, Irene
A1 Andrés Guerrero, Vanesa
A1 Pastoriza Abal, María Pilar
A1 Molina Martínez, Irene Teresa
A1 Herrero Vanrell, María Del Rocío
AB Efficient treatment of ocular diseases can be achieved thanks to the proper use of ophthalmic formulations based on emerging pharmaceutical approaches. Among them, microtechnology and nanotechnology strategies are of great interest in the development of novel drug delivery systems to be used for ocular therapy. The location of the target site in the eye as well as the ophthalmic disease will determine the route of administration (topical, intraocular, periocular, and suprachoroidal administration) and the most adequate device.In this review, we discuss the use of colloidal pharmaceutical systems (nanoparticles, liposomes, niosomes, dendrimers, and microemulsions), microparticles (microcapsules and microspheres), and hybrid systems (combination of different strategies) in the treatment of ophthalmic diseases. Emphasis has been placed in the therapeutic significance of each drug delivery system for clinical translation.
SN 2190-393X
YR 2016
FD 2016-12
LK https://hdl.handle.net/20.500.14352/18755
UL https://hdl.handle.net/20.500.14352/18755
LA eng
NO Bravo Osuna, I., Andrés Guerrero, V., Pastoria Abal, M. P. et al. «Pharmaceutical Microscale and Nanoscale Approaches for Efficient Treatment of Ocular Diseases». Drug Delivery and Translational Research, vol. 6, n.o 6, diciembre de 2016, pp. 686-707. DOI.org (Crossref), https://doi.org/10.1007/s13346-016-0336-5.
NO Ministerio de Ciencia, Innovación y Universidades (España)
NO Instituto de Salud Carlos III/Fondo Europeo de Desarrollo Regional
NO Ministerio de Sanidad (España)
NO Universidad Complutense de Madrid
DS Docta Complutense
RD 23 abr 2025