TY - JOUR AU - Cuesta Rubio, Natalia AU - Nhu, Quan M AU - Zudaire, Enrique AU - Polumuri, Swamy AU - Cuttitta, Frank AU - Vogel, Stefanie N PY - 2007 DO - 10.4049/jimmunol.178.6.3602 SN - 0022-1767 UR - https://hdl.handle.net/20.500.14352/108830 T2 - The Journal of Immunology AB - Los ratones knockout para el factor regulador de IFN-2 (IRF-2-/-) son significativamente más resistentes al tratamiento con una dosis letal de lipopolisacárido (LPS) que los compañeros de camada de genotipo salvaje, y esto se correlacionó previamente... AB - IFN regulatory factor (IRF)-2−/− mice are significantly more resistant to LPS challenge than wild-type littermates, and this was correlated with increased numbers of apoptotic Kupffer cells. To assess the generality of this observation, and to... LA - eng M2 - 3602 PB - American Association of Immunologists KW - Apoptosis KW - Macrófagos KW - IRF-2 TI - IFN regulatory factor-2 regulates macrophage apoptosis through a STAT1/3 and caspase-1-dependent mechanism. TY - journal article VL - 178 ER -