RT Conference Proceedings
T1 Biosafety of hydrogen peroxide solution to disinfect blue light-filtering contact lens.
T2 Bioseguridad de la solución de peróxido de hidrógeno para desinfectar lentes de contacto con filtro de luz azul.
A1 Sánchez Ramos, Celia
A1 Bonnin Arias, Cristina Natalia
A1 Álvarez Peregrina, Cristina
A1 Chamorro Gutiérrez, E.
AB Purpose:To establish the biocompatibility of hydrophilic lenses made of different materials, each having different absorbance levels for short wavelengths, and treated byperoxide disinfection Ever Clean® (Avizor) on in-vitro human conjunctive fibroblasts.Methods:Human conjunctive fibroblast cultures were incubated for 12 hours in three groups of blue light-filtering contact lens made by different materials (Hema 38%, Profilcon A 52% WC and Ocufilcon D 55% WC) that had been treated by peroxide disinfection Ever Clean®. Toxicity was examined by means of: 1) level of reactive oxygen species, 2) integrity of the mitochondrial membrane, 3) activation of caspase-3 and 4) activation of H2AX, compared with non-treated cells (basal control) and cells exposed to a known cytotoxic effect with H2O2 (toxicity control).
YR 2012
FD 2012-04-22
LK https://hdl.handle.net/20.500.14352/108665
UL https://hdl.handle.net/20.500.14352/108665
LA eng
DS Docta Complutense
RD 24 jun 2025