RT Journal Article
T1 Using old liver grafts for liver transplantation: Where are the limits?
A1 Jiménez Romero, Luis Carlos
A1 Caso Maestro, Óscar
A1 Cambra Molero, Félix
A1 Justo Alonso, Iago
A1 Alegre Torrado, Cristina
A1 Manrique Municio, Alejandro
A1 Calvo Pulido, Jorge
A1 Loinaz Segurola, Carmelo
A1 Moreno González, Enrique
AB The scarcity of ideal liver grafts for orthotopic liver transplantation (OLT) has led transplant teams to investigate other sources of grafts in order to augment the donor liver pool. One way to get more liver grafts is to use marginal donors, a not well-defined group which includes mainly donors > 60 years, donors with hypernatremia or macrosteatosis > 30%, donors with hepatitis C virus or hepatitis B virus positive serologies, cold ischemia time > 12 h, non-heart-beating donors, and grafts from split-livers or living-related donations. Perhaps the most practical and frequent measure to increase the liver pool, and thus to reduce waiting list mortality, is to use older livers. In the past years the results of OLT with old livers have improved, mainly due to better selection and maintenance of donors, improvements in surgical techniques in donors and recipients, and intra- and post-OLT management. At the present time, sexagenarian livers are generally accepted, but there still exists some controversy regarding the use of septuagenarian and octogenarian liver grafts. The aim of this paper is to briefly review the aging process of the liver and reported experiences using old livers for OLT. Fundamentally, the series of septuagenarian and octogenarian livers will be addressed to see if there is a limit to using these aged grafts.Jiménez-Romero C, Caso Maestro O, Cambra Molero F, Justo Alonso I, Alegre Torrado C, Manrique Municio A, Calvo Pulido J, Loinaz Segurola C, Moreno González E. Using old liver grafts for liver transplantation: Where are the limits? World J Gastroenterol 2014; 20(31): 10691-10702 [PMID: 25152573 DOI: 10.3748/wjg.v20.i31.10691]
PB Baishideng Publishing Group Inc.
SN 1007-9327
YR 2014
FD 2014-08-21
LK https://hdl.handle.net/20.500.14352/116003
UL https://hdl.handle.net/20.500.14352/116003
LA eng
NO Jiménez-Romero C, Caso Maestro O, Cambra Molero F, Justo Alonso I, Alegre Torrado C, Manrique Municio A, Calvo Pulido J, Loinaz Segurola C, Moreno González E. Using old liver grafts for liver transplantation: Where are the limits? World J Gastroenterol 2014; 20(31): 10691-10702  Jiménez-Romero C, Caso Maestro O, Cambra Molero F, Justo Alonso I, Alegre Torrado C, Manrique Municio A, Calvo Pulido J, Loinaz Segurola C, Moreno González E. Using old liver grafts for liver transplantation: Where are the limits? World J Gastroenterol 2014; 20(31): 10691-10702 [PMID: 25152573 DOI: 10.3748/wjg.v20.i31.10691]
DS Docta Complutense
RD 7 abr 2025