RT Journal Article
T1 Association of a DASH diet and magnetoencephalography in dementia-free adults with different risk levels of Alzheimer’s disease
A1 Trabado Fernández, Alfredo
A1 García Colomo, Alejandra
A1 Cuadrado Soto, Esther
A1 Peral Suárez, África
A1 Salas González, María Dolores
A1 Lorenzo Mora, Ana María
A1 Aparicio Vizuete, Aranzazu
A1 Delgado Losada, María Luisa
A1 Maestu Unturbe, Fernando
A1 López Sobaler, Ana María
AB This study explored how adherence to the DASH diet relates to electrophysiological measures in individuals at varying Alzheimer's disease (AD) risk due to family history (FH). There were 179 dementia-free subjects. DASH index was calculated, and participants were classified into different DASH adherence groups. Tertiles of relative alpha power in default mode network (DMN) regions were calculated. Multivariate logistic regression models were used to examine the association. Lower DASH adherence was associated with decreased odds of higher relative alpha power in the DMN, observed across the entire sample and specifically among those without a FH of AD. Logistic regression models indicated that participants with poorer DASH adherence had a reduced likelihood of elevated DMN alpha power, potentially influenced by vascular and amyloid-beta mechanisms. These findings underscore the dietary pattern's potential role in neural activity modulation, particularly in individuals not genetically predisposed to AD.
PB Springer Nature
SN 2509-2723
YR 2024
FD 2024-10-01
LK https://hdl.handle.net/20.500.14352/122512
UL https://hdl.handle.net/20.500.14352/122512
LA eng
NO Trabado Fernández, A., García Colomo, A., Cuadrado Soto, E., Peral Suárez, Á., Salas González, M. D., Lorenzo Mora, A. M., Aparicio, A., Delgado Losada, M. L., Maestú Unturbe, F., & López Sobaler, A. M. (2025). Association of a DASH diet and magnetoencephalography in dementia-free adults with different risk levels of Alzheimer’s disease. GeroScience, 47(2), 1747-1759. https://doi.org/10.1007/s11357-024-01361-3
NO Este artículo es la versión original del autor antes de la revisión por pares. La versión publicada puede consultarse en el siguiente enlace:https://www.doi.org/10.1007/s11357-024-01361-3
DS Docta Complutense
RD 20 ene 2026