RT Journal Article
T1 Corneal Confocal Microscopy Findings in Neuro Lyme Disease: A Case Report
A1 Cañadas Suárez, María Del Pilar
A1 García González, Montserrat
A1 Cañones Zafra, Rafael
A1 Teus Guezala, Miguel Ángel
AB Neuro Lyme disease is caused by several bacteriae of the Borreliaceae family, such as Borrelia Miyamotoi. In late stages of illness, patients with Lyme disease may develop chronic neurologic symptoms such as cognitive disturbances or small fiber peripheral neuropathy. Confocal microscopy is a non-invasive method designed to evaluate the human cornea in vivo. Thus, all the corneal layers, including the cells and the sub-basal nerve plexus, can be easily visualized and analyzed. This is the first report of the morphology of small-fiber peripheral neuropathy analyzed by confocal microscopy in a patient diagnosed of neuro Lyme disease. The decrease in the number of unmyelinated sub-basal nerve fibers with abundant presence of dendritic cells (DC) in comparison with healthy corneas strongly supports the diagnosis of small fiber peripheral neuropathy in a case of neuroborreliosis disease.
PB MDPI
SN 2075-4418
YR 2022
FD 2022-01-29
LK https://hdl.handle.net/20.500.14352/72392
UL https://hdl.handle.net/20.500.14352/72392
LA eng
DS Docta Complutense
RD 27 abr 2025