RT Journal Article T1 Beam-Shaping Extended Depth of Focus Intraocular Lens: Optical Assessment With Corneas of Increasing Spherical Aberration A1 Madrid Costa, David A1 Fernández Vega-Cueto, Luis A1 Azor-Morón, Juan Antonio A1 Vega Lerin, Fidel A1 Millán García-Varela, María Sagrario A1 Alfonso, José F. AB PURPOSE:To assess the optical quality and halo formation of a beam-shaping extended depth-of-focus (EDOF) intraocular lens (IOL) (AcrySof IQ Vivity; Alcon Laboratories, Inc) with corneas of long-range spherical aberration (SA) such as those resulting from myopic laser ablations.METHODS:The optical quality of the EDOF IOL and a reference monofocal IOL was evaluated with three corneas (A, B, and C, with SA =+0.135, +0.290, +0.540 µm, respectively, for a 5.15-mm pupil at the IOL plane). The through-focus modulation transfer function area (MTFa) curves were obtained between −5.00 and +2.00 diopters (D) defocus range. The halo was also assessed with the three corneas.RESULTS:Through-focus MTFa curves for a 4.5-mm IOL pupil showed a slight decrease in the maximum MTFa value provided by the EDOF IOL compared to the monofocal IOL in the three corneal situations (A: 45.9 vs 38.6 units; B: 41.1 vs 33.1 units, and C: 26.9 vs 23.8 units). For the 3.0-mm pupil, the EDOF IOL also had lower maximum MTFa than the monofocal IOL; however, the depth-of-focus increased to −2.20 D. With corneas A and B, the halo induced was of low energy with both IOLs. With cornea C, the EDOF IOL created a much larger and intense halo.CONCLUSIONS:The EDOF IOL provided a good distance optical performance and an extended range of focus of approximately 2.00 D, with a halo of low intensity when evaluated with a corneal SA similar to the one induced by a low to moderate myopic ablation. With a high myopic ablation, the halo induced would be of considerable size and energy. PB Slack Incorporated SN 1081-597X YR 2023 FD 2023-02-01 LK https://hdl.handle.net/20.500.14352/72980 UL https://hdl.handle.net/20.500.14352/72980 LA eng NO Madrid-Costa D, Fernández-Vega-Cueto L, Azor-Morón JA, Vega F, Millán MS, Alfonso JF. Beam-Shaping Extended Depth of Focus Intraocular Lens: Optical Assessment With Corneas of Increasing Spherical Aberration. Journal of Refractive Surgery. 2023;39(2):95-102. doi:10.3928/1081597X-20221215-02 NO Submitted: August 24, 2022; Accepted: December 15, 2022 NO Agencia Estatal de Investigación de España DS Docta Complutense RD 14 dic 2025