RT Journal Article
T1 Neural-Dural Transition at the Thoracic and Lumbar Spinal Nerve Roots: A Histological Study of Human Late-Stage Fetuses
A1 Cho, Kwang Ho
A1 Jin, Zhe-Wu
A1 Abe, Hiroshi
A1 Shibata, Shunichi
A1 Murakami, Gen
A1 Rodríguez Vázquez, José Francisco
AB Epidural blocks have been used extensively in infants. However, little histological information is available on the immature neural-dural transition. The neural-dural transition was histologically investigated in 12 late-stage (28–30 weeks) fetuses. The dural sheath of the spinal cord was observed to always continue along the nerve roots with varying thicknesses between specimens and segments, while the dorsal root ganglion sheath was usually very thin or unclear. Immature neural-dural transitions were associated with effective anesthesia. The posterior radicular artery was near the dorsal root ganglion and/or embedded in the nerve root, whereas the anterior radicular artery was separated from the nearest nerve root. The anterior radicular artery was not associated with the dural sheath but with thin mesenchymal tissue. The numbers of radicular arteries tended to become smaller in larger specimens. Likewise, larger specimens of the upper thoracic and lower lumbar segments did not show the artery. Therefore, elimination of the radicular arteries to form a single artery of Adamkiewicz was occurring in late-stage fetuses. The epidural space was filled with veins, and the loose tissue space extended ventrolaterally to the subpleural tissue between the ribs. Consequently, epidural blocks in infants require special attention although immature neural-dural transitions seemed to increase the effect.
PB Wiley
SN 2314-6133
YR 2016
FD 2016-03-16
LK https://hdl.handle.net/20.500.14352/109933
UL https://hdl.handle.net/20.500.14352/109933
LA eng
NO Cho, K. H., Jin, Z. W., Abe, H., Shibata, S., Murakami, G., & Rodríguez-Vázquez, J. F. (2016). Neural-Dural Transition at the Thoracic and Lumbar Spinal Nerve Roots: A Histological Study of Human Late-Stage Fetuses. BioMed research international, 2016, 8163519. https://doi.org/10.1155/2016/8163519
DS Docta Complutense
RD 13 abr 2025