RT Journal Article
T1 Wastewater-based epidemiology as a novel tool to evaluate human exposure to pesticides: Triazines and organophosphates as case studies
A1 Rousis, Nikolaos
A1 Gracia Lor, Emma
A1 Hernández, Félix
A1 Poretti, Francesco
A1 Santos, Miguel M
A1 Zuccato, Ettore
A1 Castiglioni, Sara
AB Production and application of pesticides have risen remarkably in the last fewdecades. Even if they provide many benefits, they can be hazardous for humans and ecosystemswhen they are not used cautiously. Human exposure to pesticides is well documented, but new approaches are needed to boost the available information. This work proposes a newapplication ofwastewater-based epidemiology (WBE) to assess the exposure of the general population to organophosphate and triazine pesticides (pyrethroid pesticides have already been validated). Several human urinary metabolites tested asWBE biomarkers,were suitable. Untreated wastewater samples fromdifferent European countries were analyzed by liquid chromatography-tandem mass spectrometry. Biomarker concentrations were converted to mass loads and used to back-calculate the local population's exposure to the parent pesticides, using specific correction factors developed in this study. Exposure to organophosphates and pyrethroids showed spatial and seasonal variations. Finally, pesticide exposure was estimated in twenty cities of ten European countries and compared with the acceptable daily intake, concluding that some populations might face health risks. The study confirms WBE as a suitable approach for assessing the average community exposure to pesticides and is a valuable complementary biomonitoring tool.WBE can provide valuable data for public health.
PB Elsevier
YR 2021
FD 2021-06
LK https://hdl.handle.net/20.500.14352/114328
UL https://hdl.handle.net/20.500.14352/114328
LA eng
NO Nikolaos I. Rousis, Emma Gracia-Lor, Félix Hernández, Francesco Poretti, Miguel M. Santos, Ettore Zuccato, Sara Castiglioni, Wastewater-based epidemiology as a novel tool to evaluate human exposure to pesticides: Triazines and organophosphates as case studies, Science of The Total Environment, Volume 793, 2021, 148618.
DS Docta Complutense
RD 7 abr 2025