RT Journal Article
T1 Multivalent Choline Dendrimers as Potent Inhibitors of Pneumococcal Cell-Wall Hydrolysis
A1 Hernandez-Rocamora, Victor
A1 Maestro García-Donas, María Beatriz
A1 de Waal, Bas
A1 Morales, María
A1 Garcia, Pedro
A1 Meijer, Bert
A1 Merx, Maarten
A1 Sanz, Jesús
AB Dendritic cell-wall mimics: Choline-binding proteins from Streptococcus pneumoniae recognize distinctive multivalent choline architectures on the bacterial cell wall. Choline-functionalized dendrimers are potent inhibitors of these essential enzymes, with a 103–104-fold higher affinity than free choline, resulting in inhibition of autolysis and cell separation in bacterial cultures at low micromolar concentrations
PB Wiley
SN 1433-7851
YR 2009
FD 2009
LK https://hdl.handle.net/20.500.14352/93420.2
UL https://hdl.handle.net/20.500.14352/93420.2
LA eng
NO Hernández‐Rocamora, Víctor M., et al. «Multivalent Choline Dendrimers as Potent Inhibitors of Pneumococcal Cell‐Wall Hydrolysis». Angewandte Chemie International Edition, vol. 48, n.o 5, enero de 2009, pp. 948-51. https://doi.org/10.1002/anie.200803664.
NO Escuela Valenciana de Estudios para la Salud
NO Fundación Salvat Inquifarma
NO Ministerio de Educación y Ciencia (España)
NO Instituto de Salud Carlos III
NO Comunidad de Madrid
NO Netherlands Organisation for Scientific Research
DS Docta Complutense
RD 26 abr 2025