RT Journal Article
T1 A Population-Based Study of Diabetes during Pregnancy in Spain (2009–2015): Trends in Incidence, Obstetric Interventions, and Pregnancy Outcomes
A1 López De Andrés, Ana Isabel
A1 Pérez Farinós, Napoleón
A1 Hernández Barrera, Valentín
A1 Palomar Gallego, María A.
A1 Carabantes Alarcón, David
A1 Zamorano León, José Javier
A1 Miguel Díez, Javier De
A1 Jiménez García, Rodrigo
AB Background: We examined trends in incidence and outcomes in women with existing type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM) and gestational diabetes mellitus (GDM) compared with a control group without diabetes.Methods: This was an observational, retrospective epidemiological study using the National Hospital Discharge Database.Results: There were 2,481,479 deliveries in Spain between 2009 and 2015 (5561 mothers with T1DM, 4391 with T2DM, and 130,980 with GDM). Incidence and maternal age of existing diabetes and GDM increased over time. Women with T2DM were more likely to have obstetric comorbidity (70.12%) than those with GDM (60.28%), T1DM (59.45%), and no diabetes (41.82%). Previous cesarean delivery, preeclampsia, smoking, hypertension, and obesity were the most prevalent risk factors in all types of diabetes. Women with T1DM had the highest rate of cesarean delivery (Risk Ratio (RR) 2.34; 95% Confidence Interval (CI) 2.26–2.43) and prolonged maternal length of stay. Labor induction was higher in T2DM (RR 1.99; 95% CI 1.89–2.10). Women with T1DM had more severe maternal morbidity (RR 1.97; 95% CI 1.70–2.29) and neonatal morbidity (preterm birth, RR 3.32; 95% CI 3.14–3.51, and fetal overgrowth, RR 8.05; 95% CI 7.41–8.75).Conclusions: existing and GDM incidence has increased over time. We found differences in the prevalence of comorbidities, obstetric risk factors, and the rate of adverse obstetric outcomes among women with different types of diabetes. Pregnant women with diabetes have the highest risk of adverse pregnancy outcomes.
PB MDPI
SN 2077-0383
YR 2020
FD 2020-02-21
LK https://hdl.handle.net/20.500.14352/8201
UL https://hdl.handle.net/20.500.14352/8201
LA eng
NO López De Andrés, A. I., Pérez Farinós, N., Hernández Barrera, V. et al. «A Population-Based Study of Diabetes during Pregnancy in Spain (2009–2015): Trends in Incidence, Obstetric Interventions, and Pregnancy Outcomes». Journal of Clinical Medicine, vol. 9, n.o 2, febrero de 2020, p. 582. DOI.org (Crossref), https://doi.org/10.3390/jcm9020582.
NO Instituto de Salud Carlos III/Fondo Europeo de Desarrollo Regional
DS Docta Complutense
RD 9 abr 2025