RT Journal Article
T1 New psychoactive substances in several European populations assessed by wastewater-based epidemiology
A1 Castiglioni, Sara
A1 Salgueiro González, Noelia
A1 Bijlsma, Lubertus
A1 Celma, Alberto
A1 Gracia Lor, Emma
A1 Beldean Galea, Mihail Simion
A1 Mackulak, Tomas
A1 Emke, Erik
A1 Heath, Ester
A1 Kasprzyk-Hordern, Barbara
A1 Petkovic, Andjelka
A1 Poretti, Francesco
A1 Rangelov, Jeliaz
A1 Santos, Miguel M
A1 Sremacki, Maja
A1 Styszko, Katarzyna
A1 Hernández, Félix
A1 Zuccato, Ettore
AB Wastewater-based epidemiology (WBE) can be a useful tool to face some of the existing challenges in monitoring the use of new psychoactive substances (NPS), as it can provide objective and updated infor- mation. This Europe-wide study aimed to verify the suitability of WBE for investigating the use of NPS. Selected NPS were monitored in urban wastewater by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS). The main classical illicit drugs were monitored in the same samples to compare their levels with those of NPS. Raw composite wastewater samples were collected in 2016 and 2017 in 14 European countries (22 cities) following best practice sampling protocols. Methcathinone was most frequent ( > 65% of the cities), followed by mephedrone ( > 25% of the cities), and only mephedrone, methcathinone and methylone were found in both years. This study depicts the use of NPS in Europe, confirming that it is much lower than the use of classical drugs. WBE proved able to assess the qualita- tive and quantitative spatial and temporal profiles of NPS use. The results show the changeable nature of the NPS market and the importance of large WBE monitoring campaigns for selected priority NPS. WBE is valuable for complementing epidemiological studies to follow rapidly changing profiles of use of drugs.
PB Elsevier
YR 2021
FD 2021-02
LK https://hdl.handle.net/20.500.14352/114389
UL https://hdl.handle.net/20.500.14352/114389
LA eng
NO Sara Castiglioni, Noelia Salgueiro-González, Lubertus Bijlsma, Alberto Celma, Emma Gracia-Lor, Mihail Simion Beldean-Galea, Tomáš Mackuľak, Erik Emke, Ester Heath, Barbara Kasprzyk-Hordern, Andjelka Petkovic, Francesco Poretti, Jeliaz Rangelov, Miguel M. Santos, Maja Sremački, Katarzyna Styszko, Felix Hernández, Ettore Zuccato, New psychoactive substances in several European populations assessed by wastewater-based epidemiology, Water Research, Volume 195, 2021, 116983, ISSN 0043-1354, https://doi.org/10.1016/j.watres.2021.116983.
NO Ministerio de Ciencia, Innovación y Universidades
DS Docta Complutense
RD 5 abr 2025