RT Journal Article T1 Peripheral melt of flap after laser in situ keratomileusis A1 Castillo, Alfredo A1 Díaz Valle, David A1 Gutierrez, Angel R. A1 Toledano, Nicolás A1 Romero, Francisco AB BACKGROUND: Laser in situ keratomileusis (LASIK) is an effective procedure to correct myopia. It may have complications related to the flap, such as epithelial ingrowth and stromal melt. METHODS: We report on a patient who developed extensive epithelial ingrowth and partial keratolysis of the flap following LASIK. This complication was treated by lifting the flap and removing the epithelium from within the interface. RESULTS: Progressive keratolysis (stromal melt) can result irregular astigmatism and loss of vision as well as photophobia and ciliary injection. The pathogenesis is not completely understood although the epithelial ingrowth in the interface is always present, and epithelial-stromal interaction with production of proteases may be involved. CONCLUSION: Epithelial ingrowth may develop in the lamellar interface after LASIK and be associated with melting of the edge of the flap. This undesirable complication can be successfully managed with early surgical removal of the epithelium and proper attachment of the flap. PB Slack Journals SN 1081-597X SN 1081-597X YR 1998 FD 1998-01-10 LK https://hdl.handle.net/20.500.14352/112583 UL https://hdl.handle.net/20.500.14352/112583 LA eng NO Castillo A, Diaz-Valle D, Gutierrez AR, Toledano N, Romero F. Peripheral melt of flap after laser in situ keratomileusis. J Refract Surg. 1998 Jan-Feb;14(1):61-3. doi: 10.3928/1081-597X-19980101-12. DS Docta Complutense RD 10 abr 2025