RT Journal Article
T1 Biological activity of Fe(III) aquo-complexes towards ferric chelate reductase (FCR)
A1 Escudero, R.
A1 Gómez Gallego, María Del Mar
A1 Romano, S.
A1 Fernández, I.
A1 Gutiérrez Alonso, Ángel
A1 Sierra, M.A.
A1 López Rayo, S.
A1 Nadal, P.
A1 Lucena, J.J.
AB In this study we have obtained experimental evidence that confirms the high activity of aquo complexes III and IV towards the enzyme FCR, responsible for the reduction of Fe(iii) to Fe(ii) in the process of iron acquisition by plants. The in vivo FCR assays in roots of stressed cucumber plants have shown a higher efficiency of the family of complexes III and a striking structure-activity relationship with the nature of the substituent placed in a phenyl group far away from the metal center. The results obtained in this work demonstrate that all the aquo compounds tested interact efficiently with the enzyme FCR and hence constitute a new concept of iron chelates that could be of great use in agronomy.
PB The Royal Society of Chemistry
YR 2012
FD 2012
LK https://hdl.handle.net/20.500.14352/117278
UL https://hdl.handle.net/20.500.14352/117278
LA eng
NO Escudero, R., Gómez-Gallego, M., Romano, S., Fernández, I., Gutiérrez-Alonso, Á., Sierra, M. A., López-Rayo, S., Nadal, P., & Lucena, J. J. (2012). Biological activity of Fe(iii) aquo-complexes towards ferric chelate reductase (FCR). Organic and Biomolecular Chemistry, 10(11), 2272-2281.
NO Ministerio de Ciencia, Innovación y Universidades
NO Comunidad de Madrid
DS Docta Complutense
RD 18 dic 2025