RT Journal Article
T1 Trends and Sex Differences in Hospitalizations and Mortality in Parkinson’s Disease in Spain (2010–2019): A Nationwide Population-Based Study
A1 Gómez Mayordomo, Víctor
A1 Alonso Frech, Fernando
A1 Hernández Barrera, Valentín
A1 Carabantes Alarcón, David
A1 Zamorano León, José Javier
A1 López De Andrés, Ana Isabel
A1 Jiménez García, Rodrigo
AB The incidence of hospitalizations of Parkinson´s disease (PD) in Spain suffered a steady rise from 1997 to 2012. However, data on the trends during the following decade (2010–2019) are lacking. Hospital admissions with a primary and secondary diagnosis of PD were selected using the Spanish National Hospital Discharge Database (SNHDD) for the period 2010–2019. The primary endpoint was the incidence of hospitalizations and in-hospital mortality, stratified in biannual periods. The incidence of PD hospitalizations increased progressively over time from 81.25 cases in 2010–2011 to 94.82 cases in 2018–2019 per 100,000 inhabitants. Male sex, age and comorbidity also increased progressively in PD inpatients. PD as a comorbid condition presented a higher increment (annual percentage of change, APC +1.71%, p < 0.05) than PD as the main reason of hospitalization (APC +1.26%, p < 0.05). In the multivariate regression model, factors associated with mortality were male sex (OR = 1.15, 95% CI 1.01–1.35), age (>80 years, OR = 12.76, 95% CI 3.96–29.64) and comorbidity (Charlson index ≥ 2, OR 1.77, 95% CI 1.69–1.85). Adjusted mortality by age, sex, comorbidity and diagnostic position remained stable. In conclusion, PD hospitalizations in Spain have increased, with a parallel increment in mean age, male sex and higher comorbidities. However, adjusted mortality remains unchanged. The burden of this disease may increase the complexity and costs of hospital care in the future.
PB MDPI
SN 2077-0383
YR 2023
FD 2023
LK https://hdl.handle.net/20.500.14352/72318
UL https://hdl.handle.net/20.500.14352/72318
LA spa
NO Gómez Mayordomo, V., Alonso Frech, F., Hernández Barrera, V. et al. «Trends and Sex Differences in Hospitalizations and Mortality in Parkinson’s Disease in Spain (2010–2019): A Nationwide Population-Based Study». Journal of Clinical Medicine, vol. 12, n.o 3, enero de 2023, p. 902. DOI.org (Crossref), https://doi.org/10.3390/jcm12030902.
NO This research was funded by Convenio V-PRICIT de la Comunidad de Madrid y la Universidad Complutense de Madrid (“Programa de Excelencia para el Profesorado Universitario” INV.AY.20.2021.1E126). Universidad Complutense de Madrid. Grupo de Investigación en Epidemiología de las Enfermedades Crónicas de Alta Prevalencia en España (970970).
NO Convenio V-PRICIT
NO Universidad Complutense de Madrid: Grupo de Investigación en Epidemiología de las Enfermedades Crónicas de Alta Prevalencia en España
DS Docta Complutense
RD 19 abr 2025