TY - JOUR AU - Villegas Díaz, María Rocío AU - Baeza García, Alejandro AU - Nouredinne, Achraf AU - Durfee, Paul N AU - Butler, Kimberly S AU - Agola, Jacob Ongudi AU - Brinker, C.Jeffrey AU - Vallet Regí, María Dulce Nombre PY - 2018 DO - 10.1021/acs.chemmater.7b03128 SN - ISSN: 0897-4756 UR - https://hdl.handle.net/20.500.14352/11947 T2 - Chemistry of Materials AB - The high density of the extracellular matrix in solid tumors is an important obstacle to nanocarriers for reaching deep tumor regions and has severely limited the efficacy of administrated nanotherapeutics. The use of proteolytic enzymes prior to... LA - spa PB - American Chemical Society KW - Mesoporous silica nanoparticles KW - Supported lipid bilayers KW - Protocells KW - Penetration KW - Targeting KW - 3D tumoral tissue model TI - Multifunctional Protocells for Enhanced Penetration in 3D Extracellular Tumoral Matrices. TY - journal article VL - 30 ER -