RT Journal Article T1 Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights A1 Vallet Regí, María Dulce Nombre A1 Colilla Nieto, Montserrat A1 Izquierdo Barba, Isabel A1 Manzano García, Miguel AB This manuscript reviews the recent progress on mesoporous silica nanoparticles as drug delivery systems. Their intrinsic structural, textural and chemical features permit to design versatile multifunctional nanosystems with the capability to target the diseased tissue and release the cargo on demand upon exposition to internal or external stimuli. The degradation rate of these nanocarriers in diverse physiological fluids is overviewed obeying their significance for their potential translation towards clinical applications. To conclude, the balance between the benefits and downsides of this revolutionary nanotechnological tool is also discussed. PB MDPI SN 1420-3049 YR 2017 FD 2017-12-25 LK https://hdl.handle.net/20.500.14352/18309 UL https://hdl.handle.net/20.500.14352/18309 LA eng NO RESEARCHER ID M-3378-2014 (María Vallet Regí)ORCID 0000-0002-6104-4889 (María Vallet Regí)RESEARCHER ID N-4628-2014 (Montse Colilla Nieto)RESEARCHER ID M-9921-2014 (Isabel Izquierdo Barba)ORCID 0000-0002-4139-4646 (Isabel Izquierdo Barba)ORCID 0000-0003-1961-4160 (Montse Colilla Nieto)RESEARCHER ID K-3719-2014 (Miguel Manzano García)ORCID 0000-0001-6238-6111 (Miguel Manzano García) NO Unión Europea. H2020 NO Ministerio de Economía y Competitividad (MINECO) DS Docta Complutense RD 22 mar 2025