TY  - JOUR
AU  - Ramos Alonso, Eva
AU  - Palomino-Antolín, Alejandra
AU  - Bartolini, Manuela
AU  - Iriepa, Isabel
AU  - Moraleda, Ignacio
AU  - Diez-Iriepa, Daniel
AU  - Samadi, Abdelouahid
AU  - Cortina, Carol V.
AU  - Chioua, Mourad
AU  - Egea, Javier
AU  - Romero Martínez, Manuel Alejandro
AU  - Marco-Contelles, José
PY  - 2019
DO  - 10.3390/molecules24081503
SN  - 1420-3049
UR  - https://hdl.handle.net/20.500.14352/12527
T2  - Molecules
AB  - We report the synthesis and relevant pharmacological properties of the quinoxalinetacrine (QT) hybrid QT78 in a project targeted to identify new non-hepatotoxic tacrine derivatives for Alzheimer’s disease therapy. We have found that QT78 is less toxic...
LA  - eng
M2  - 1503
PB  - MDPI
KW  - Alzheimer’s disease
KW  - cholinesterase inhibitor
KW  - hepatotoxicity
KW  - molecular modeling
KW  - neuroprotection
KW  - quinoxalines
KW  - quinoxalinetacrines
KW  - tacrine
TI  - QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer’s Disease Therapy
TY  - journal article
VL  - 24
ER  -