TY - JOUR AU - Albert-Gasco, Hector AU - Smith, Heather L. AU - Álvarez Castelao, Beatriz AU - Swinden, Dean AU - Halliday, Mark AU - Janaki-Raman, Sudha AU - Butcher, Adrian J. AU - Mallucci, Giovanna R. PY - 2024 DO - 10.1093/brain/awad313 SN - 1460-2156 UR - https://hdl.handle.net/20.500.14352/103601 T2 - Brain AB - The unfolded protein response (UPR) is rapidly gaining momentum as a therapeutic target for protein misfolding neurodegenerative diseases, in which its overactivation results in sustained translational repression leading to synapse loss and... LA - eng M2 - 649 PB - Oxford University Press KW - Neurodegeneration KW - UPR/ISR KW - Nascent proteome KW - Translational repression KW - Trazodone KW - Mitochondria KW - Synapses TI - Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration TY - journal article VL - 147 ER -