RT Journal Article T1 Influence of the extraction method on the bioactive phenolic compounds recovery from food industry by-products A1 Gil Martín, Emilio A1 Forbes Hernández, Tamara A1 Romero Martínez, Manuel Alejandro A1 Cianciosi, Danila A1 Giampieri, Francesca A1 Battino, Maurizio AB Agro-foodindustries generate colossal amounts of non-edible waste and by-products, easily accessible as raw materials for up-cycling active phytochemicals. Phenolic compounds are particularly relevant in this field given their abundance in plant residues and the market interest of their functionalities (e.g. natural antioxidant activity) as part of nutraceutical, cosmetological and biomedical formulations. In “bench-to-bedside” achievements, sample extraction is essential because valorization benefits from matrix desorption and solubilization of targeted phytocompounds. Specifically, the composition and polarity of the extractant, the optimal sample particle size and sample:solvent ratio, as well as pH, pressure and temperature are strategic for the release and stability of mobilized species. On the other hand, current green chemistry environmental rules require extraction approaches that eliminate polluting consumables and reduce energy needs. Thus, the following pages provide an update on advanced technologies for the sustainable and efficient recovery of phenolics from plant matrices. PB Elsevier SN 0308-8146 YR 2021 FD 2021-12-23 LK https://hdl.handle.net/20.500.14352/113309 UL https://hdl.handle.net/20.500.14352/113309 LA eng NO Emilio Gil-Martín, Tamara Forbes-Hernández, Alejandro Romero, Danila Cianciosi, Francesca Giampieri, Maurizio Battino, Influence of the extraction method on the recovery of bioactive phenolic compounds from food industry by-products, Food Chemistry, Volume 378, 2022, 131918, https://doi.org/10.1016/j.foodchem.2021.131918. DS Docta Complutense RD 5 abr 2025