RT Journal Article
T1 Effects of L-Glutamine Supplementation during the Gestation of Gilts and Sows on the Offspring Development in a Traditional Swine Breed
A1 Vázquez Gómez, Marta
A1 García-Contreras, Consolación
A1 Astiz, Susana
A1 Torres-Rovira, Laura
A1 Pesantez-Pacheco, José Luis
A1 De las Heras Molina, Ana
A1 Castro Madrigal, Teresa
A1 López Bote, Clemente José
A1 Óvilo, Cristina
A1 González-Bulnes, Antonio
A1 Isabel Redondo, Beatriz
AB The use of amino acids during pregnancy, such as glutamine (Gln), seems to be a promising strategy in selected swine breeds to improve the offspring prenatal development. The main goal of the current study was to assess the development of the offspring from parity 1–3 sows of a traditional breed, which were supplemented with 1% glutamine after Day 35 of gestation, under farm conditions. A total of 486 (288 treated) piglets from 78 (46 treated) Iberian sows were used. At birth and slaughterhouse, fatty acid composition, metabolism, and mTOR pathway gene expression were analyzed. At birth, treated newborns showed greater amounts of specific amino acids in plasma, such as glutamine, asparagine, or alanine, and Σn-3 fatty acids in cellular membranes than control newborns. The expression of genes belonging to mTOR Complex 1 was also higher in treated piglets with normal birth-weight. However, these findings did not improve productive traits at birth or following periods in litters from supplemented gilts (parity 1) or sows (parities 2–3). Thus, further research is needed to properly understand the effects of prenatal glutamine supplementation, particularly in traditional swine breeds.
PB MDPI
SN 2076-2615
YR 2021
FD 2021-03-22
LK https://hdl.handle.net/20.500.14352/93732
UL https://hdl.handle.net/20.500.14352/93732
LA eng
NO Vázquez-Gómez, M.; García-Contreras, C.; Astiz, S.; Torres-Rovira, L.; Pesantez-Pacheco, J.L.; Heras-Molina, A.; Castro Madrigal, T.; López-Bote, C.; Óvilo, C.; González-Bulnes, A.; et al. Effects of L-Glutamine Supplementation during the Gestation of Gilts and Sows on the Offspring Development in a Traditional Swine Breed. Animals 2021, 11, 903. https://doi.org/10.3390/ani11030903
NO Ministry of Economy and Competitiveness (project AGL2016-79321-C2-2-R and AGL2019-108695RB-C31), co-funded by FEDER
NO AHM, CGC and MVG were supported by the Spanish Government (AHM: FPI National Program BES-2017-080541; CGC: FPI BES-2014-070464; MVG: FPU National Program FPU014/01285).
DS Docta Complutense
RD 20 dic 2025