TY - JOUR AU - Vilchez, David AU - Ros, Susana AU - Cifuentes, Daniel AU - Pujadas, Lluís AU - Vallès, Jordi AU - García-Fojeda García-Valdecasas, María Belén AU - Criado-García, Olga AU - Fernández-Sánchez, Elena AU - Medraño-Fernández, Iria AU - Domínguez, Jorge AU - García-Rocha, Mar AU - Soriano, Eduardo AU - Rodríguez de Córdoba, Santiago AU - Guinovart, Joan PY - 2007 DO - 10.1038/nn1998 SN - 1097-6256 UR - https://hdl.handle.net/20.500.14352/98244 T2 - Nature Neuroscience AB - Glycogen synthesis is normally absent in neurons. However, inclusion bodies resembling abnormal glycogen accumulate in several neurological diseases, particularly in progressive myoclonus epilepsy or Lafora disease. We show here that mouse neurons... LA - eng M2 - 1407 PB - Springer Nature KW - Glycogen KW - Neurons KW - Lafora disease KW - Glycogen synthase KW - Laforin KW - Malin KW - Protein targeting to glycogen KW - Protein phosphatase 1 KW - Proteasome-dependent degradation TI - Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy TY - journal article VL - 10 ER -