RT Journal Article
T1 Influence of grape variety and their phenolic composition on vasorelaxing activity of young red wines
A1 Ortega Hernández-Agero, María Teresa
A1 De la Hera, Elena
A1 Carretero Accame, María Emilia
A1 Gómez-Serranillos Cuadrado, María Pilar
A1 Naval López, María Victoria
A1 Villar Del Fresno, Angel María
A1 Prodánov Prodánov, Marín
A1 Vacas, Visitación
A1 Arroyo Casado, Teresa
A1 Hernández García, María Teresa
A1 Estrella Pedrola, María Isabel
AB Red wine has been reported to exert beneficial effects in preventing cardiovascular diseases probably due to their polyphenols constituents. The vasorelaxant capacity and phenolic composition of four monovarietal young red wines Merlot, Tempranillo, Garnacha and Cabernet-Sauvignon obtained from grapes from 2004 vintage, cultivated under the same climatic and agricultural conditions, wine-making technology and storage conditions, were determined using vascular reactivity assay in rat aortic and high-performance liquid chromatography, respectively. Primary cultures of vascular smooth muscle cells from Wistar rats were also used to evaluate their survival prevention activity as well. Every studied wine present vasorelaxation effect, but the higher value corresponds to the analyzed Merlot wine, especially rich in phenolic compounds, mainly catechins and oligomeric proanthocyanidins and anthocyanin glycosides. This study further demonstrated previous investigations about the phenolic composition of wines relation with their vasorelaxation activity
PB Springer
YR 2008
FD 2008
LK https://hdl.handle.net/20.500.14352/99297
UL https://hdl.handle.net/20.500.14352/99297
LA eng
NO 'Ortega T, De La Hera E, Carretero ME,  Gómez-Serranillos P, Naval MV, Villar AM, Prodanov M, Vacas V, Arroyo T, Hernández T,  Estrella I. Influence of grape variety and their phenolic composition on vasorelaxing activity of young red wines. Eur Food Res Technol 2008; 227: 1641–1650'
NO Ministerio de Ciencia, Innovación y Universidades (España)
NO Consejo Superior de Investigaciones Científicas (España)
DS Docta Complutense
RD 9 abr 2025