RT Journal Article
T1 Effects of physical activity/exercise on tear film characteristics and dry eye associated symptoms: A literature review
A1 Navarro López, Sergio
A1 Moya Ramón, Manuel
A1 Gallar, Juana
A1 Carracedo Rodríguez, Juan Gonzalo
A1 Aracil Marco, Adiolfo
AB Purpose: To conduct a review of the literature in order to identify the potential association between physical activity or exercise and the objective signs and/or subjective symptoms of dry-eye disease.Methods: A review of PubMed and Web of Science databases was performed, according to the PRISMA guidelines. The papers included in the review addressed the relationship of physical activity or exercise with dry-eye associated signs (changes in tear volume, osmolarity or biochemical composition) and/or subjective symptoms.Results: A total of 16 papers were included. In eight, the changes in tear film volume, osmolarity and/or biochemical composition were studied after a single, acute bout of aerobic exercise. In another eight, changes in dry-eye associated symptoms were studied in relation to the habitual practice of physical activity or to prescribed exercise programmes. Acute responses of the tear film to exercise included: a) an increase of tear volume, without an increase of the tear break-up time; b) a trend to increase tear osmolarity, although within its physiological range; and c) a reduced concentration of several cytokines, and other molecular markers of inflammation or oxidative stress. Long-term exposure to physical activity or exercise programmes was associated with relief of dry-eye associated symptoms and a trend to increased tear break-up time.Conclusions: Despite a high heterogeneity in the studied population, study designs and methods, the current body of evidence suggests a potential role for physical activity as a modulatory stimulus for the proper functioning of the tear film and/or the relief of dry-eye symptoms.
PB Elsevier
YR 2023
FD 2023-05-10
LK https://hdl.handle.net/20.500.14352/87410
UL https://hdl.handle.net/20.500.14352/87410
LA eng
NO Ministerio de Ciencia, Innovación y Universidades de España
NO Unión Europea
NO Universidad Miguel Hernández de Elche (España)
DS Docta Complutense
RD 10 abr 2025