TY  - JOUR
AU  - Lehmann, Guillermo L.
AU  - Ginsberg, Michael
AU  - Nolan, Daniel J.
AU  - Rodríguez, Cristina
AU  - Martínez González, José
AU  - Zeng, Shemin
AU  - Voigt, Andrew P.
AU  - Mullins, Robert F.
AU  - Rafii, Shahin
AU  - Rodriguez Boulan, Enrique
AU  - Benedicto, Ignacio
PY  - 2022
DO  - 10.3390/cells11192975
SN  - 2073-4409
UR  - https://hdl.handle.net/20.500.14352/72276
T2  - Cells
AB  - Alpha-2-macroglobulin (A2M) is a protease inhibitor that regulates extracellular matrix (ECM) stability and turnover. Here, we show that A2M is expressed by endothelial cells (ECs) from human eye choroid. We demonstrate that retinal pigment epithelium...
LA  - eng
M2  - 2975
PB  - MDPI
KW  - Alpha-2-macroglobulin (A2M)
KW  - Retinal pigment epithelium (RPE)
KW  - Vascular endothelialgrowth factor-A (VEGF-A)
KW  - Endothelial cells (ECs)
KW  - Extracellular matrix (ECM)
KW  - Matrix metalloproteinase2 (MMP-2)
KW  - Protease inhibitor
KW  - Age-related macular degeneration (AMD)
KW  - Bruch’s membrane
TI  - Retinal Pigment Epithelium-Secreted VEGF-A Induces Alpha-2-Macroglobulin Expression in Endothelial Cells
TY  - journal article
VL  - 11
ER  -