RT Journal Article
T1 Analysis of heart rate variability in individuals affected by amyotrophic lateral sclerosis
A1 Maset Roig, Rosa
A1 Caplliure Llopis, Jordi
A1 de Bernardo, Nieves
A1 Privado Zamorano, Jesús
A1 Alarcón Jiménez, Jorge
A1 Martín Ruiz, Julio
A1 Botella Navas, Marta
A1 Villarón Casales, Carlos
A1 Sancho Cantus, David
A1 de la Rubia Ortí, José Enrique
AB Introduction: Amyotrophic lateral sclerosis (ALS) produces alterations in the autonomic nervous system (ANS), which explains the cardiac manifestations observed in patients. The assessment of heart rate variability (HRV) is what best reflects the activity of the ANS on heart rate. The Polar H7 Bluetooth® device proves to be a non-invasive and much faster technology than existing alternatives for this purpose. Objective: The goal of this study is to determine HRV using Polar  H7 Bluetooth technology in ALS patients, comparing the obtained measurements with values from healthy individuals. Method: The sample consisted of 124 participants: 68 diagnosed with ALS and 56 healthy individuals. Using Polar H7 Bluetooth technology and the ELITE HRV application, various HRV measurements were determined for all participants, specifically the HRV index, RMSSD, RMSSD LN, SDNN index, PNN50, LF, HF, LF/HF ratio, HR average, and HF peak frequency. Results: Statistically significant differences were observed between ALS patients and healthy individuals in the HRV index, RMSSD, RMSSD LN, SDNN index, PNN50, HF, and LF, where healthy individuals exhibited higher scores. For the HR average, the ALS group showed a higher value. Values were similar when comparing men and women with ALS, with only a higher HF peak frequency observed in women. Conclusion: The Polar H7 Bluetooth® device is effective in determining heart rate variability alterations in ALS, being a promising prognostic tool for the disease.
PB MDPI
YR 2024
FD 2024-04-07
LK https://hdl.handle.net/20.500.14352/129246
UL https://hdl.handle.net/20.500.14352/129246
LA eng
NO Maset-Roig, R.; Caplliure-Llopis, J.; de Bernardo, N.; Privado, J.; Alarcón-Jiménez, J.; Martín-Ruiz, J.; Botella-Navas, M.; Villarón-Casales, C.; Sancho-Cantus, D.; de la Rubia Ortí, J.E. Analysis of Heart Rate Variability in Individuals Affected by Amyotrophic Lateral Sclerosis. Sensors 2024, 24, 2355. https://doi.org/10.3390/s24072355
NO Universidad Católica de Valencia
DS Docta Complutense
RD 31 dic 2025