TY  - THES
AU  - Aparicio Blanco, Juan
A3  - Torres Suárez, Ana Isabel
PY  - 2019
UR  - https://hdl.handle.net/20.500.14352/16842
AB  - Diseases affecting the central nervous system (CNS) should be regarded as a major health challenge due to their steadily rising incidences and to the current lack of effective treatments given the hindrance to brain drug delivery imposed by the...
AB  - Las patologías que afectan al sistema nervioso central representan un desafío terapéutico por su incidencia creciente y la limitación del acceso a sistema nervioso central de la mayoría de fármacos administrados por vía sistémica por parte de la...
LA  - eng
PB  - Universidad Complutense de Madrid
KW  - Active targeting
KW  - Blood-cerebrospinal barrier
KW  - Brain drug delivery
KW  - Brain targeting
KW  - Brain theranostics
KW  - Brain tumors
KW  - Cannabidiol
KW  - Cannabinoids
KW  - Cell culture
KW  - Central nervous system tumors
KW  - Chemotherapy
KW  - Clinical trials
KW  - Extended-release
KW  - Glioma targeting
KW  - In vitro blood-brain barrier model
KW  - Lipid nanocapsule
KW  - Lipid nanocarriers
KW  - Local delivery
KW  - Low-energy method
KW  - Nanocarrier
KW  - Nanoimaging
KW  - Nanomedicine
KW  - Parallel artificial membrane permeability assay
KW  - Passive targeting
KW  - Permeability
KW  - Phase inversion temperature
KW  - Rational design
KW  - Systemic delivery
KW  - Fármacos
KW  - Barrera hematoencefálica
KW  - Sistema nervioso central
KW  - Nanocápsulas lipídicas con cannabidiol
TI  - Development of lipid nanocapsules as a strategy to overcome the passage across the blood-brain barrier of drug substances acting on the central nervous system
T2  - Desarrollo de nanocápsulas lipídicas como estrategia para facilitar el paso a través de la barrera hematoencefálica de fármacos que actúan a nivel del sistema nervioso central
M3  - doctoral thesis
ER  -