RT Journal Article T1 Malaria Hidden in a Patient with Diffuse Large-B-Cell Lymphoma and Sickle-Cell Trait A1 Linares Gómez, María A1 Albizua, Enriqueta A1 Méndez, Darío A1 Rubio, José María A1 Martínez Serna, Alejandra A1 Martínez, Miguel A1 Salto, Efren A1 Puyet Catalina, Antonio A1 Díez Martín, Amalia A1 Martínez López, Joaquín A1 Bautista Santa Cruz, José Manuel AB We report a case of an African patient with sickle cell trait who was diagnosed in Spain with B-cell lymphoma. Blood smears were negative for malaria, and no plasmodium antigens were detected in the blood. To treat his lymphoma, the patient underwent chemotherapy and autologous stem cell transplantation. Following a splenectomy due to a worsening condition, he developed clinical malaria with detectable parasitemia. This case suggests that the humoral response and parasite removal by the spleen may afford protection from overt disease and may even help maintain subclinical human reservoirs of the disease. SN 0095-1137 YR 2011 FD 2011 LK https://hdl.handle.net/20.500.14352/94537 UL https://hdl.handle.net/20.500.14352/94537 LA eng NO Linares Gómez, M., Albizua, E., Méndez, D. et al. «Malaria Hidden in a Patient with Diffuse Large-B-Cell Lymphoma and Sickle-Cell Trait». Journal of Clinical Microbiology, vol. 49, n.o 12, diciembre de 2011, pp. 4401-04. DOI.org (Crossref), https://doi.org/10.1128/JCM.00911-11. DS Docta Complutense RD 21 abr 2025