TY - JOUR AU - Rodríguez Escudero, María Isabel AU - Fernández-Acero Bascones, Teresa AU - Jiménez Cid, Víctor AU - Molina, María PY - 2018 DO - 10.1038/s41598-018-25717-w SN - 2045-2322 UR - https://hdl.handle.net/20.500.14352/13362 T2 - Scientific Reports AB - The Akt protein kinase is the main transducer of phosphatidylinositol-3,4,5-trisphosphate (PtdIns3,4,5P) signaling in higher eukaryotes, controlling cell growth, motility, proliferation and survival. By co-expression of mammalian class I... LA - eng M2 - 7732 PB - Nature Research KW - PI3K KW - Saccharomyces cerevisiae KW - Eisosomes KW - Fluorescent reporter KW - Heterologous expression KW - Humanized yeast KW - Kinase inhibitors KW - P110α KW - Phosphoinositides KW - Septins TI - Heterologous mammalian Akt disrupts plasma membrane homeostasis by taking over TORC2 signaling in Saccharomyces cerevisiae. TY - journal article VL - 8 ER -