RT Journal Article
T1 Clinical effects of the adjunctive use of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in the management of peri-implant diseases: A randomized clinical trial
A1 Pulcini, Alberto
A1 Bollaín, Juan
A1 Sanz Sánchez, Ignacio
A1 Figuero Ruiz, Elena
A1 Alonso Álvarez, Bettina María
A1 Sanz Alonso, Mariano
A1 Herrera González, David
A2 Wiley online library, 
AB Aim: To evaluate the efficacy of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse, as an adjunct to professionally and patient-administered mechanical plaque removal, in the treatment of peri-implant mucositis (PiM).Material and methods: Patients displaying PiM in, at least, one implant were included in this randomized, double-blinded, clinical trial. Subjects received professional prophylaxis (baseline and 6 months) and were instructed to regular oral hygiene practices and to rinse, twice daily, with the test or placebo mouth rinses, during one year. Clinical, radiographic and microbiological outcomes were evaluated at baseline, 6 and 12 months. Disease resolution was defined as absence of bleeding on probing (BOP). Data were analysed by repeated measures ANOVA, Student's t and chi-square tests.Results: Fifty-four patients were included and 46 attended the final visit (22 in control and 24 in test group). In the test group, there was a 24.49% greater reduction in BOP at the buccal sites (95% confidence interval [3.65-45.34%]; p = 0.002) than in controls. About 58.3% of test implants and 50% controls showed healthy peri-implant tissues at final visit (p > 0.05).Conclusions: The use of the test mouth rinse demonstrated some adjunctive benefits in the treatment of PiM. Complete disease resolution could not be achieved in every case.Trial registration: ClinicalTrials.gov NCT03533166.Keywords: chlorhexidine; dental implant; mouth rinse; peri-implant diseases; peri-implant mucositis.
PB Wiley online library
SN 0022-0345
YR 2019
FD 2019
LK https://hdl.handle.net/20.500.14352/102445
UL https://hdl.handle.net/20.500.14352/102445
LA eng
NO Pulcini A, Bollaín J, Sanz-Sánchez I, Figuero E, Alonso B, Sanz M, Herrera D. Clinical effects of the adjunctive use of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in the management of peri-implant diseases: A randomized clinical trial. J Clin Periodontol. 2019 Mar;46(3):342-353. doi: 10.1111/jcpe.13088. PMID: 30779246.
DS Docta Complutense
RD 11 abr 2025