RT Journal Article
T1 HIV medical care interruption among people living with HIV in Spain, 2004-2020
A1 Izquierdo, Rebeca
A1 Rava, Marta
A1 Moreno García, Estela
A1 Blanco, José Ramón
A1 Asensi, Víctor
A1 Cervero, Miguel
A1 Curran, Adrian
A1 Rubio García, Rafael
A1 Iribarren, José Antonio
A1 Jarrín, Inmaculada
AB Objective: We estimated the incidence rate of HIV medical care interruption (MCI) and its evolution over a 16-year-period, and identified associated risk factors among HIV-positive individuals from the Cohort of the Spanish AIDS Research Network in 2004-2020.Design: We included antiretroviral-naive individuals aged at least 18 years at enrolment, recruited between January 1, 2004, and August 30, 2019, and followed-up until November 30, 2020.Methods: Individuals with any time interval of at least 15 months between two visits were defined as having a MCI. We calculated the incidence rate (IR) of having at least one MCI and used multivariable Poisson regression models to identify associated risk factors.Results: Of 15 274 individuals, 5481 (35.9%) had at least one MCI. Of those, 2536 (46.3%) returned to HIV care after MCI and 3753 (68.5%) were lost to follow-up at the end of the study period. The incidence rate (IR) of MCI was 7.2/100 person-years (py) [95% confidence interval (CI): 7.0-7.4]. The annual IR gradually decreased from 20.5/100 py (95% CI: 16.4-25.6) in 2004 to 4.9/100 py (95% CI: 4.4-5.5) in 2014, a slight increase was observed between 2015 and 2018, reaching 9.3/100 py (95% CI: 8.6-10.2) in 2019. Risk factors for MCI included younger age, lower educational level, having contracted HIV infection through injecting drug use or heterosexual intercourse, having been born outside of Spain, and CD4 + cell count >200 cell/μl, viral load <100 000 and co-infection with hepatitis C virus at enrolment.Conclusions: Around a third of individuals had at least one MCI during the follow-up. Identified predictors of MCI can help health workers to target and support most vulnerable individuals.
PB Lippincott, Williams & Wilkins
SN 0269-9370
YR 2023
FD 2023-07-01
LK https://hdl.handle.net/20.500.14352/105599
UL https://hdl.handle.net/20.500.14352/105599
LA eng
NO Izquierdo R, Rava M, Moreno-García E, Blanco JR, Asensi V, Cervero M, Curran A, Rubio R, Iribarren JA, Jarrín I; Cohort of the Spanish HIV/AIDS Research Network (CoRIS). HIV medical care interruption among people living with HIV in Spain, 2004-2020. AIDS. 2023 Jul 1;37(8):1277-1284
NO Instituto de Salud Carlos III (España)
DS Docta Complutense
RD 9 abr 2025