RT Journal Article
T1 María Teresa Miras Portugal: a pioneer in the study of purinoceptors in chromaffin cells
T2 María Teresa Miras Portugal: pionera en el estudio de los purinoceptores de las células cromafines
A1 Rodríguez Artalejo, Antonio
A1 Barahona Gomáriz, María Victoria
A1 Llorente, Celia
A1 Olivos Ore, Luis Alcides
A1 Arribas Blázquez, Marina
AB María Teresa Miras Portugal devoted most of her scientific life to the study of purinergic signalling. In an important part of her work, she used a model system: the chromaffin cells of the adrenal medulla. It was in these cells that she identified diadenosine polyphosphates, from which she proceeded to the study of adrenomedullary purinome: nucleotide synthesis and degradation, adenosine transport, nucleotide uptake into chromaffin granules, exocytotic release of nucleotides and autocrine regulation of chromaffin cell function via purinoceptors. This short review will focus on the current state of knowledge of the purinoceptors of adrenal chromaffin cells, a subject to which María Teresa made seminal contributions and which she continued to study until the end of her scientific life.
PB Springer
SN 1573-9538
YR 2023
FD 2023-03-21
LK https://hdl.handle.net/20.500.14352/94873
UL https://hdl.handle.net/20.500.14352/94873
LA eng
NO CRUE-CSIC agreement with Springer Nature
NO Ministerio de Ciencia e Innovación of Spain (PID2019-109155RB-I00)
DS Docta Complutense
RD 29 abr 2025