RT Journal Article T1 Reconstruction of a rostral maxillary defect by two custom-made titanium implants following a partial maxillectomy for treatment of squamous cell carcinoma in a dog A1 Fraile Fernández, Andrés A1 Fuertes Recuero, Manuel A1 Espinel Rupérez, Jorge A1 Cárdenas Osuna, Alejandro A1 Ruano Barreda, Ricardo A1 Horcajada Garcia, Javier A1 Ortiz Díez, Gustavo AB This case report describes the reconstruction of a rostral maxillary defect by two custom-made titanium implants following a rostral partial maxillectomy for treatment of squamous cell carcinoma (SCC) in a seven-year-old dog. An incisional biopsy and CT scan were performed to establish the diagnosis, to plan possible surgery, and to assess the margins of the tumour. The patient had no radiographic signs of metastasis at the time of diagnosis. An oblique rostral partial maxillectomy with two custom-made titanium plates was chosen as an effective oncological treatment and to maintain the cosmetic appearance. A first custom implant was designed to support the cheek and lips, and a second implant was designed to replace part of the hard palate and serve as a base for the palatal mucosal flap. Surgical treatment combined with toceranib phosphate and cimicoxib therapy provided a survival time of at least 1700 days, as the patient is still alive at time of publication. Further research is warranted to determine the oncological and cosmetic efficacy of this surgical technique for treatment of SCC in a larger group of dogs PB Springer SN 0165-7380 YR 2025 FD 2025 LK https://hdl.handle.net/20.500.14352/119030 UL https://hdl.handle.net/20.500.14352/119030 LA eng NO Fraile-Fernandez, A., Fuertes-Recuero, M., Espinel-Rupérez, J., Cárdenas-Osuna, A., Barreda, R. R., Horcajada-Garcia, J., & Ortiz-Diez, G. (2025). Reconstruction of a rostral maxillary defect by two custom-made titanium implants following a partial maxillectomy for treatment of squamous cell carcinoma in a dog. Veterinary research communications, 49(2), 80. https://doi.org/10.1007/s11259-025-10643-w NO Author contributions: All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by MFR, AFF, JER, ACO, RRB, JHG, and GOD. The first draft of the manuscript was written by MFR, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript. DS Docta Complutense RD 6 abr 2025