RT Journal Article
T1 Reliability and Minimal Detectable Change for Respiratory Muscle Strength Measures in Individuals With Multiple Sclerosis
A1 Aguilar Zafra, Sandra
A1 Fabero Garrido, Raúl
A1 Del Corral Núñez-Flores, Tamara
A1 López De Uralde Villanueva, Ibai Julio
AB Background and Purpose: The test-retest reliability and minimal detectable changes (MDCs) for respiratory muscle strength measures have not been determined in individuals with multiple sclerosis (MS). This study determined the test-retest reliability and MDCs for specific respiratory muscle strength measures, as well as their associations with health-related quality of life (HRQoL), disability, dyspnea, and physical activity level measures in this population. In addition, the study examined differences in respiratory muscle strength between different degrees of disability.Methods: Sixty-one individuals with MS attended 2 appointments separated by 7 to 10 days. Respiratory muscle strength was evaluated by maximal inspiratory and expiratory pressures (MIP/MEP), HRQoL by EuroQol-5D-5L (index and visual analog scale [EQ-VAS]), disability by the Expanded Disability Status Scale, dyspnea by the Medical Research Council scale, and physical activity levels by the International Physical Activity Questionnaire.Results: Respiratory muscle strength measures had excellent test-retest reliability (ICC ≥ 0.92). The MDC for MIP is 15.42 cmH 2 O and for MEP is 17.84 cmH 2 O. Participants with higher respiratory muscle strength (MIP/MEP cmH 2 O and percentage of predicted values) had higher HRQoL ( r = 0.54-0.62, P < 0.01, EQ-5D-5L index; r = 0.30-0.42, P < 0.05, EQ-VAS); those with higher expiratory muscle strength (cmH 2 O and percentage of predicted values) had lower levels of disability ( r ≤ -0.66) and dyspnea ( r ≤ -0.61). There were differences in respiratory muscle strength between different degrees of disability ( P < 0.01; d ≥ 0.73).Discussion and conclusion: Respiratory muscle strength measures provide excellent test-retest reliability in individuals with MS. MDCs can be interpreted and applied in the clinical setting. Low respiratory muscle strength can contribute to a poor HRQoL; specifically, expiratory muscle strength appears to have the strongest influence on disability status and dyspnea.
PB Lippincott, Williams & Wilkins
SN 1557-0576
YR 2023
FD 2023-11-24
LK https://hdl.handle.net/20.500.14352/103233
UL https://hdl.handle.net/20.500.14352/103233
LA eng
NO Aguilar-Zafra, Sandra PT, MSc; Fabero-Garrido, Raúl PT, MSc; del Corral, Tamara PT, PhD; López-de-Uralde-Villanueva, Ibai PT, PhD. Reliability and Minimal Detectable Change for Respiratory Muscle Strength Measures in Individuals With Multiple Sclerosis. Journal of Neurologic Physical Therapy 48(2):p 94-101, April 2024. | DOI: 10.1097/NPT.0000000000000462
DS Docta Complutense
RD 7 abr 2025