TY - JOUR AU - Fiorini, Claudia AU - Cordani, Marco AU - Padroni, Chiara AU - Blandino, Giovanni AU - Di Agostino, Silvia AU - Donadelli, Massimo PY - 2015 DO - 10.1016/j.bbamcr.2014.10.003 SN - 0167-4889 UR - https://hdl.handle.net/20.500.14352/94640 T2 - Biochimica et Biophysica Acta (BBA) - Molecular Cell Research AB - Pancreatic adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths worldwide; PDAC is characterized by poor prognosis, resistance to conventional chemotherapy and high mortality rate. TP53 tumor suppressor gene is frequently mutated... LA - eng M2 - 89 PB - Elsevier KW - Pancreatic adenocarcinoma KW - Gemcitabine KW - Mutant p53 KW - Gain-of-function (GOF) KW - Autophagy KW - p53-reactivating molecules TI - Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine TY - journal article VL - 1853 ER -