RT Journal Article T1 Survey of a Crimean-Congo hemorrhagic fever enzootic focus in Spain (2011-2015). A1 Negredo, A A1 Habela, M.A A1 Ramírez de Arellano, E A1 Díez, F A1 Lasala, F A1 López, P A1 Sarriá, A A1 Labiod, N A1 Calero Bernal, Rafael A1 Arenas, M A1 Tenorio, A A1 Estrada Peña, A A1 Sánchez Seco, M AB During 2011–2015, we conducted a Crimean-Congo hemorrhagic fever virus (CCHFV) survey in captured ticks that were feeding mainly on wild and domestic ungulates in Spain, where presence of this virus had been reported previously. We detected CCHFV RNA in Hyalomma lusitanicum and H. marginatum ticks for 3 of the 5 years. The rate of infected ticks was 2.78% (44/1,579), which was similar to those for other countries in Europe with endemic foci for CCHFV (Kosovo, Bulgaria, and Albania). These data confirm the established spread of CCHFV into western Europe. Phylogenetic study of the small RNA segment showed Africa-3 clade as the only genotype identified, although we observed cocirculation of genetic variants during 2011 and 2015. We could not rule out genetic reassortments because of lack of sequence data for the medium and large RNA segments of the virus genome. PB Centre for Disease Control and Prevention YR 2019 FD 2019 LK https://hdl.handle.net/20.500.14352/110266 UL https://hdl.handle.net/20.500.14352/110266 LA eng NO Negredo, A., Habela, M. Á., Ramírez de Arellano, E., Diez, F., Lasala, F., López, P., Sarriá, A., Labiod, N., Calero-Bernal, R., Arenas, M., Tenorio, A., Estrada-Peña, A., & Sánchez-Seco, M. P. (2019). Survey of Crimean-Congo Hemorrhagic Fever Enzootic Focus, Spain, 2011-2015. Emerging infectious diseases, 25(6), 1177–1184. https://doi.org/10.3201/eid2506.180877 NO Instituto de Salud Carlos III ( España) DS Docta Complutense RD 12 abr 2025