RT Journal Article
T1 Clonal Spread of Levofloxacin-Resistant Streptococcus pneumoniae Invasive Isolates in Madrid, Spain, 2007 to 2009
A1 Rodríguez-Avial Infante, Iciar
A1 Ramos, Belén
A1 Ríos Dueñas, Esther
A1 Cercenado Mansilla, Emilia
A1 Ordobás, María
A1 Sanz Fernández, Juan Carlos
AB Among 1,349 Streptococcus pneumoniae invasive isolates, 45 (3.3%) were levofloxacin resistant. Serotype distribution was as follows: 8 (n = 32 isolates), 19A (n = 4 isolates), 7F (n = 3 isolates), 9V (n = 2 isolates), 10A (n = 1 isolate), 19F (n = 1 isolate), 6B (n = 1 isolate), and nontypeable (n = 1 isolate). Levofloxacin-resistant isolates had dual mutations in the gyrA and parC genes. Serotype 8 strains corresponded to a capsular switching of the Sweden15A-25 clone. Levofloxacin resistance was also detected among multiresistant (ST27619A, Spain9V-ST156, ST8819F, and ST15426B) and among usually antibiotic-susceptible (Netherlands7F-ST191, ST120119A, and ST263910A) clones.
PB American Society for Microbiology
SN 0066-4804
YR 2011
FD 2011-04-28
LK https://hdl.handle.net/20.500.14352/112751
UL https://hdl.handle.net/20.500.14352/112751
LA eng
NO Rodríguez-Avial IRamos B, Ríos E, Cercenado EOrdobás M, Sanz JC, 2011. Clonal Spread of Levofloxacin-Resistant Streptococcus pneumoniae Invasive Isolates in Madrid, Spain, 2007 to 2009. Antimicrob Agents Chemother 55:. https://doi.org/10.1128/aac.01380-10
DS Docta Complutense
RD 19 abr 2025