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oai:docta.ucm.es:20.500.14352/1014342025-09-02T13:52:12Zcom_20.500.14352_14col_20.500.14352_15

Miguel Díez, Javier De Albaladejo Vicente, Romana Palacios-Ceña, Domingo Carabantes Alarcón, David Zamorano León, José Javier López Herranz, Marta López De Andrés, Ana Isabel 2024-02-14T15:40:18Z 2024-02-14T15:40:18Z 2020 de Miguel-Diez J, Albaladejo-Vicente R, Palacios-Ceña D, Carabantes-Alarcon D, Zamorano-Leon JJ, Lopez-Herranz M, Lopez-de-Andres A. The Impact of COPD in Trends of Urinary Tract Infection Hospitalizations in Spain, 2001-2018: A Population-Based Study Using Administrative Data. J Clin Med. 2020 Dec 9;9(12):3979. doi: 10.3390/jcm9123979. PMID: 33316870; PMCID: PMC7763854. 10.3390/jcm9123979 https://hdl.handle.net/20.500.14352/101434 2077-0383 https://doi.org/10.3390/jcm9123979 Background: To examine trends in incidence and outcomes of urinary tract infections (UTIs) among men and women with or without chronic obstructive pulmonary disease (COPD), and to identify the predictors for in-hospital mortality (IHM). (2) Methods: We included patients (aged ≥40 years) who were hospitalized with UTIs between 2001 and 2018. Data were collected from the Spanish National Hospital Discharge Database. (3) Results: We identified 748,458 UTI hospitalizations, 6.53% with COPD. The UTIs incidence increased over time. It was 1.55 times higher among men COPD patients than among non-COPD men (incidence rate ratio (IRR) 1.55; 95% CI 1.53-1.56). The opposite happened in women with COPD compared to non-COPD women (IRR 0.30; 95% CI 0.28-0.32). IHM was higher in men with COPD than non-COPD men (5.58% vs. 4.47%; p < 0.001) and the same happened in women (5.62% vs. 4.92%; p < 0.001). The risk of dying increased with age and comorbidity, but the urinary catheter was a protective factor among men (OR 0.75; 95% CI 0.64-0.89). Multivariable analysis showed a significant reduction in the IHM over time for men and women with COPD. Suffering from COPD only increased the risk of IHM among men (OR 1.07; 95% CI 1.01-1.13). (4) Conclusions: The incidence of UTIs increased over time. Suffering COPD increased the risk of IHM among men, but not among women. eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 International The Impact of COPD in Trends of Urinary Tract Infection Hospitalizations in Spain, 2001–2018: A Population-Based Study Using Administrative Data journal article