2026-08-16T14:13:57Zhttps://docta.ucm.es/rest/oai/request
oai:docta.ucm.es:20.500.14352/1014552024-02-16T00:47:43Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense author Paradas Lara, Irene author Casado Gómez, Inmaculada author Martín, Conchita author Martínez Sanz, Elena author López Gordillo, Yamila author González, Pablo author Rodríguez Bobada, Cruz author Chamorro, Manuel author Arias, Pablo author Maldonado Bautista, Estela author Ortega Aranegui, Ricardo author Berenguer, Beatriz author Martínez Álvarez, María Concepción 2024-02-15T08:48:07Z 2024-02-15T08:48:07Z 2014 Paradas-Lara, I., Casado-Gómez, I., Martín, C., Martínez-Sanz, E., López-Gordillo, Y., González, P., ... & Martínez-Álvarez, C. (2014). Maxillary growth in a congenital cleft palate canine model for surgical research. Journal of Cranio-Maxillofacial Surgery, 42(1), 13-21. 1010-5182 10.1016/J.JCMS.2013.01.032 https://hdl.handle.net/20.500.14352/101455 1878-4119 https://www.sciencedirect.com/science/article/pii/S1010518213000486?via%3Dihub https://pubmed.ncbi.nlm.nih.gov/23434237/ We have recently presented the Old Spanish Pointer dog, with a 15-20% spontaneous congenital cleft palate rate, as a unique experimental model of this disease. This study aimed to describe the cleft palate of these dogs for surgical research purposes and to determine whether congenital cleft palate influences maxillofacial growth. Seven newborn Old Spanish Pointer dogs of both sexes, comprising a cleft palate group (n = 4) and a normal palate group (n = 3), were fed using the same technique. Macroscopic photographs and plaster casts from the palate, lateral radiographs and computer tomograms of the skull were taken sequentially over 41 weeks, starting at week 5. The cleft morphology, the size and the tissue characteristics in these dogs resembled the human cleft better than current available animal models. During growth, the cleft width varies. Most of the transverse and longitudinal measures of the palate were statistically lower in the cleft palate group. The cleft palate group showed hypoplasia of the naso-maxillary complex. This model of congenital cleft palate seems suitable for surgical research purposes. A reduced maxillofacial pre- and post-natal development is associated to the congenital cleft palate in the Old Spanish Pointer dog. eng Maxillary growth in a congenital cleft palate canine model for surgical research journal article 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URL https://docta.ucm.es/bitstreams/3e5ea4ba-bab3-475d-b8a1-a43027632f6d/download File MD5 5d0a225febc3aa3a2a6d2aeb5beb0d3c 1344439 application/pdf 2014 Paradas et al, 2014 (J Cranmaxfac Surg).pdf