2026-06-01T02:10:22Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/1038942025-03-18T15:33:06Zcom_20.500.14352_14col_20.500.14352_15

Comorbidity patterns and mortality among hospitalized patients with psychiatric disorders and COVID-19 Sánchez Rico, Marina Rezaei, Katayoun Delgado Álvarez, Alfonso Limosin, Frédéric Hoertel, Nicolas Alvarado Izquierdo, Jesús María COVID-19 Psychiatric disorders Comorbidity Mortality Clustering Mood disorders Neuropsicología 3205.07 Neurología Objective: To examine the association between psychiatric and non-psychiatric comorbidity and 28-day mortality among patients with psychiatric disorders and COVID-19. Methods: We performed a multicenter observational retrospective cohort study of adult patients with psychiatric disorders hospitalized with laboratory-confirmed COVID-19 at 36 Greater Paris University hospitals (January 2020-May 2021) (N=3,768). First, we searched for different subgroups of patients according to their psychiatric and non-psychiatric comorbidities through cluster analysis. Next, we compared 28-day all-cause mortality rates across the identified clusters, while taking into account sex, age, and the number of medical conditions. Results: We found 5 clusters of patients with distinct psychiatric and non-psychiatric comorbidity patterns. Twenty-eight-day mortality in the cluster of patients with mood disorders was significantly lower than in other clusters. There were no significant differences in mortality across other clusters. Conclusions: All psychiatric and non-psychiatric conditions may be associated with increased mortality in patients with psychiatric disorders and COVID-19. The lower risk of death among patients with mood disorders might be in line with the potential beneficial effect of certain antidepressants in COVID-19, but requires further research. These findings may help identify at-risk patients with psychiatric disorders who should benefit from vaccine booster prioritization and other prevention measures. Depto. de Psicobiología y Metodología en Ciencias del Comportamiento Fac. de Psicología TRUE pub 2024-05-10T12:07:45Z 2024-05-10T12:07:45Z 2023 journal article AM https://hdl.handle.net/20.500.14352/103894 1516-4446 10.47626/1516-4446-2023-3076 1809-452X eng Sánchez-Rico M, Rezaei K, Delgado-Álvarez A, Limosin F, Hoertel N, Alvarado JM. Comorbidity Patterns and Mortality Among Hospitalized Patients with Psychiatric Disorders and COVID-19. Braz J Psychiatry.2022;0(0):1-23 https://doi.org/10.47626/1516-4446-2023-3076 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ open access application/pdf Associaçao Brasileira de Psiquiatria (ABP)