2026-06-30T03:13:54Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/1040752025-03-18T12:42:14Zcom_20.500.14352_14col_20.500.14352_15

00925njm 22002777a 4500 dc Lozano Borregón, Daniel author Larraga, Vicente author Vallet Regí, María Dulce Nombre author Manzano García, Miguel author 2023-06-09 Vaccines represent one of the most significant advancements in public health since they prevented morbidity and mortality in millions of people every year. Conventionally, vaccine technology focused on either live attenuated or inactivated vaccines. However, the application of nanotechnology to vaccine development revolutionized the field. Nanoparticles emerged in both academia and the pharmaceutical industry as promising vectors to develop future vaccines. Regardless of the striking development of nanoparticles vaccines research and the variety of conceptually and structurally different formulations proposed, only a few of them advanced to clinical investigation and usage in the clinic so far. This review covered some of the most important developments of nanotechnology applied to vaccine technologies in the last few years, focusing on the successful race for the preparation of lipid nanoparticles employed in the successful anti-SARS-CoV-2 vaccines. Lozano, D.; Larraga, V.; Vallet-Regí, M.; Manzano, M. An Overview of the Use of Nanoparticles in Vaccine Development. Nanomaterials 2023, 13, 1828. https://doi.org/10.3390/nano13121828 10.3390/nano13121828 https://hdl.handle.net/20.500.14352/104075 2079-4991 https://doi.org/10.3390/nano13121828 An overview of the use of nanoparticles in vaccine development