2026-06-27T23:12:26Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/1087472025-09-08T14:48:39Zcom_20.500.14352_14col_20.500.14352_15

Fañani, Agustina Arcos-Álvarez, Belén Banegas, Pamela Rocha, Luciana Monge-Corredor, Julia González Rubio, Ramón Guzmán Solís, Eduardo Lucia, Alejandro 2024-10-08T10:11:29Z 2024-10-08T10:11:29Z 2024 10.1016/j.colsurfa.2024.135474 https://hdl.handle.net/20.500.14352/108747 https://doi.org/10.1016/j.colsurfa.2024.135474 https://www.sciencedirect.com/journal/colloids-and-surfaces-a-physicochemical-and-engineering-aspects The ternary system water/eugenol/poloxamer 407 can form a variety of phases that are strongly influenced by the mixture composition and the thermal history of the system. In this study, we investigated the stabilization of emulsion and gel-like systems in which eugenol is encapsulated in a poloxamer 407 matrix. Our results reveal the complex interplay between poloxamer 407 and eugenol compositions in the stabilization single-phase systems at 25ºC. Increasing concentrations of poloxamer were found to incorporate higher amounts of eugenol into emulsion-like dispersions, effectively preventing coalescence and Ostwald ripening. However, high concentrations of poloxamer 407 induced gelation of these dispersions, resulting in eugenol-loaded poloxamer 407 gels. The thermal annealing of the emulsions at 65°C for 1 h followed by equilibration at room temperature allows the extension of the compositional range for the formation of homogeneous single-phase systems providing a strategy to modulate the phase diagram of the ternary system. Additionally, the encapsulation of hydrophobic pesticides in gel-like matrices was investigated, showing uniform distribution and consistent loading capacity (approximately 0.70 % w/w) across different pesticides which may contribute to facilitate the environmental distribution and efficacy of the encapsulated molecules. This research highlights the potential of eugenol/poloxamer 407-based systems as an environmentally friendly platform for the encapsulation and delivery of hydrophobic active molecules, offering a versatile solution for various applications. eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 International Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms journal article